Characterisation of Liposomes Using Complementary Techniques
Liposomes have been attractive delivery systems for decades due to their composition of natural biological lipids and structural resemblance to cell membranes suggesting metabolic compatibility, low toxicity, overall expectations of biocompatibility and lack of a strong immune response.
They comprise spherical vesicles with an aqueous core enclosed by one or more phospholipid bilayers or lamellae and are frequently classified based on their size, polydispersity, and number of bilayers. Control over these parameters has remained a challenge with most preparation methods and is further p>accentuated when moving from a laboratory to industrial scale.
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